New JASN paper out on neuronal regulation of kidney function and inflammation

https://jasn.asnjournals.org/content/early/2021/06/18/ASN.2021010110

We show that neurons maintain perfusion and filtration of kidney. Consequently, renal denervation, an invasive intervention to treat drug-resistant arterial hypertension, influences concomitant inflammatory diseases. Deposition of circulating nephritic material is higher, and hence antibody- and endotoxin-induced kidney injury was aggravated in mice.