A High-Salt Diet Compromises Antibacterial Neutrophil Responses through Hormonal Perturbation.
Jobin K, Stumpf NE, Schwab S, Eichler M, Neubert P, Rauh M, Adamowski M, Babyak O, Hinze D, Sivalingam S, Weisheit C, Hochheiser K, Schmidt SV, Meissner M, Garbi N, Abdullah Z, Wenzel U, Hölzel M, Jantsch J, Kurts C. Sci. Transl. Med. 2020, 12 (536), eaay3850.
PMID: 32213629
Crosstalk between Sentinel and Helper Macrophages Permits Neutrophil Migration into Infected Uroepithelium.
Schiwon M, Weisheit C, Franken L, Gutweiler S, Dixit A, Meyer-Schwesinger C, Pohl JM, Maurice NJ, Thiebes S, Lorenz K, Quast T, Fuhrmann M, Baumgarten G, Lohse MJ, Opdenakker G, Bernhagen J, Bucala R, Panzer U, Kolanus W, Gröne HJ, Garbi N, Kastenmüller W, Knolle PA, Kurts C*, Engel DR*. Cell 2014, 156 (3), 456–468.
* Authors contributed equally
PMID: 24485454
Exclusive CX3CR1 Dependence of Kidney DCs Impacts Glomerulonephritis Progression.
Hochheiser K, Heuser C, Krause TA, Teteris S, Ilias A, Weisheit C, Hoss F, Tittel AP, Knolle PA, Panzer U, Engel DR, Tharaux PL, Kurts C. J. Clin. Invest. 2013, 123 (10), 4242–4254.
PMID: 23999431
Alternative Cross-Priming through CCL17-CCR4-Mediated Attraction of CTLs toward NKT Cell–Licensed DCs.
Semmling V, Lukacs-Kornek V, Thaiss CA, Quast T, Hochheiser K, Panzer U, Rossjohn J, Perlmutter P, Cao J, Godfrey DI,Savage PB, Knolle PA, Kolanus W, Förster I, Kurts C. Nat. Immunol. 2010, 11 (4), 313–320.
PMID: 20190758
Distinct Pathways of Antigen Uptake and Intracellular Routing in CD4 and CD8 T Cell Activation.
Burgdorf S, Kautz A, Böhnert V, Knolle PA, Kurts C. Science 2007, 316 (5824), 612–616.
PMID: 17463291
The Endosomal System of Primary Human Vascular Endothelial Cells and Albumin–FcRn Trafficking.
Pannek A, Becker-Gotot J, Dower SK, Verhagen AM, Gleeson PA. J. Cell Sci. 2023, 136 (15), jcs260912. https://doi.org/10.1242/jcs.260912.
PMID: 37565427
Fate Mapping Reveals Compartment-Specific Clonal Expansion of Mononuclear Phagocytes during Kidney Disease
Yin J, Mei Q, Prinz M, Abdullah Z, Panzer U, Li J, Von Vietinghoff S, Kurts C. Kidney Int. 2023, S0085253823004015. https://doi.org/10.1016/j.kint.2023.04.031.
PMID: 37290602
Cigarette Smoke Depletes Alveolar Macrophages and Delays Clearance of Legionella Pneumophila.
Fleischmann M, Jarnicki AG, Brown AS, Yang C, Anderson GP, Garbi N, Hartland EL, van Driel IR, Ng GZ. Am. J. Physiol. Lung Cell. Mol. Physiol. 2023. https://doi.org/10.1152/ajplung.00268.2022.
PMID: 36719079
Interferon-Induced IL-10 Drives Systemic T-Cell Dysfunction during Chronic Liver Injury.
Hackstein CP, Spitzer J, Symeonidis K, Horvatic H, Bedke T, Steglich B, Klein S, Assmus LM, Odainic A, Szlapa J, Kessler N, Beyer M, Schmithausen R, Latz E, Flavell RA, Garbi N, Kurts C, Kümmerer BM, Trebicka J, Roers A, Huber S, Schmidt SV, Knolle P.A, Abdullah Z. J. Hepatol. 2023, S0168827823001587. https://doi.org/10.1016/j.jhep.2023.02.026.
PMID: 36870611
Complex Regulation of Alarmins S100A8/A9 and Secretion via Gasdermin D Pores Exacerbates Autoinflammation in Familial Mediterranean Fever.
Jorch SK, McNally A, Berger P, Wolf J, Kaiser K, Chetrusca Covash A, Robeck S, Pastau I, Fehler O, Jauch-Speer SL, Hermann S, Schäfers M, Van Gorp H, Kanneganti A, Dehoorne J, Haerynck F, Penco F, Gattorno M, Chae JJ, Kubes P, Lamkanfi M, Wullaert A, Sperandio M, Vogl T, Roth J, Austermann J. J. Allergy Clin. Immunol. 2023, S0091674923002257. https://doi.org/10.1016/j.jaci.2023.01.037.
PMID: 36822481
Potentially Improved Response of COVID-19 Vaccinated Nasopharyngeal Cancer Patients to Combination Therapy with Anti-PD-1 Blockade and Chemotherapy.
Hua Y J, Liu YL, Wen K, Kurts C, Wu H, Mei Q, Li J. Ann. Oncol. 2022, S0923753422041886. https://doi.org/10.1016/j.annonc.2022.10.002
PMID: 36216192
Immune Tolerance against Infused FVIII in Hemophilia A Is Mediated by PD-L1+ Regulatory T Cells.
Becker-Gotot J, Meissner M, Kotov V, Jurado-Mestre B, Maione A, Pannek A, Albert T, Flores C, Schildberg FA, Gleeson PA, Reipert BM, Oldenburg J, Kurts C. J. Clin. Invest. 2022 https://doi.org/10.1172/JCI159925.
PMID: 36107620
Monocyte-Derived Macrophages Aggravate Pulmonary Vasculitis via CGAS/STING/IFN-Mediated Nucleic Acid Sensing.
Kessler N, Viehmann SF, Krollmann C, Mai K, Kirschner KM, Luksch H, Kotagiri P, Böhner AMC, Huugen D, de Oliveira Mann CC, Otten S, Weiss SAI, Zillinger T, Dobrikova K, Jenne DE, Behrendt R, Ablasser A, Bartok E, Hartmann G, Hopfner KP, Lyons PA, Boor P, Rösen-Wolff A, Teichmann LL, Heeringa P, Kurts C, Garbi N. J. Exp. Med. 2022, 219 (10), e20220759.
PMID: 35997679
Generation of an Alpaca Serum That Induces Immune-Mediated Crescentic Glomerulonephritis in Mice.
Dhana E, Klaus D, Böhner A, Schmidt F, von Vietinghoff S, Boor P, Djudjaj S, Kurts C. J. Immunol. Methods 2022, 507, 113310
PMID: 35787393
Impact of COVID-19 vaccination on the use of PD-1 inhibitor in treating patients with cancer: a real-world study
Mei Q, Hu G, Yang Y, Liu B, Yin J, Li M, Huang Q, Tang X, Böhner A, Bryant A, Kurts C, Yuan X, Li, J. J Immunother Cancer 2022 Mar;10(3):e004157.
PMID: 35264438
Health Issues and Immunological Assessment Related to Wuhan’s COVID-19 Survivors: A Multicenter Follow-Up Study.
Mei Q, Wang F, Yang Y, Hu G, Guo S, Zhang Q, Bryant A, Zhang L, Kurts C, Wei L, Yuan X, Li, J. Front. Med. 2021, 8, 617689.
PMID: 34026775
Regulation and Function of CX3CR1 and Its Ligand CX3CL1 in Kidney Disease.
von Vietinghoff S, Kurts C.
PMID: 34009468
Sodium and Its Manifold Impact on Our Immune System.
Jobin K, Müller DN, Jantsch J, Kurts C. Trends Immunol. 2021, 42 (6), 469–479.
PMID: 33962888
Survival Factors and Metabolic Pathogenesis in Elderly Patients (≥65) With COVID-19: A Multi-Center Study.
Mei Q, Wang AY, Bryant A, Yang Y, Li M, Wang F, Du S, Kurts C, Wu P, Ma K, Wu L, Chen H, Luo J, Li Y, Hu G, Yuan X, Li J. Front. Med. 2021, 7, 595503.
PMID: 33585504
Vascular Pathologies in Chronic Kidney Disease: Pathophysiological Mechanisms and Novel Therapeutic Approaches.
Düsing P, Zietzer A, Goody PR, Hosen MR, Kurts C, Nickenig G, Jansen F. J. Mol. Med. 2021, 99 (3), 335–348.
PMID: 33481059
A High-Salt Diet Compromises Antibacterial Neutrophil Responses through Hormonal Perturbation.
Jobin K, Stumpf NE, Schwab S, Eichler M, Neubert P, Rauh M, Adamowski M, Babyak O, Hinze D, Sivalingam S, Weisheit C, Hochheiser K, Schmidt SV, Meissner M, Garbi N, Abdullah Z, Wenzel U, Hölzel M, Jantsch J, Kurts C. Sci. Transl. Med. 2020, 12 (536), eaay3850.
PMID: 32213629
Splenic Red Pulp Macrophages Cross-Prime Early Effector CTL That Provide Rapid Defense against Viral Infections.
Enders M, Franken L, Philipp MS, Kessler N, Baumgart AK, Eichler M, Wiertz EJH, Garbi N, Kurts C. J. Immunol. 2020, 204 (1), 87–100.
PMID: 31776205
Development and Validation of Prognostic Model for Predicting Mortality of COVID-19 Patients in Wuhan, China.
Mei Q, Wang AY, Bryant A, Yang Y, Li M, Wang F, Zhao JW, Ma K, Wu L, Chen H, Luo J, Du S, Halfter K, Li Y, Kurts C, Hu G, Yuan X, Li J. Sci. Rep. 2020, 10 (1), 22451
PMID: 33384422
Pathogen-Induced Tissue-Resident Memory TH17 (TRM17) Cells Amplify Autoimmune Kidney Disease.
Krebs CF, Reimers D, Zhao Y, Paust HJ, Bartsch P, Nuñez S, Rosemblatt MV, Hellmig M, Kilian C, Borchers A, Enk LUB, Zinke M, Becker M, Schmid J, Klinge S, Wong MN, Puelles VG, Schmidt C, Bertram T, Stumpf N, Hoxha E, Meyer-Schwesinger C, Lindenmeyer MT, Cohen CD, Rink M, Kurts C, Franzenburg S, Koch-Nolte F, Turner JE, Riedel JH, Huber S, Gagliani N, Huber TB, Wiech T, Rohde H, Bono MR, Bonn S, Panzer U, Mittrücker HW. Sci. Immunol. 2020, 5 (50).
PMID: 32769171
NCX1 Represents an Ionic Na+ Sensing Mechanism in Macrophages.
Neubert P, Homann A, Wendelborn D, Bär AL, Krampert L, Trum M, Schröder A, Ebner S, Weichselbaum A, Schatz V, Linz P, Veelken R, Schulte-Schrepping J, Aschenbrenner AC, Quast T, Kurts C, Geisberger S, Kunzelmann K, Hammer K, Binger KJ, Titze J, Müller DN, Kolanus W, Schultze JL, Wagner S, Jantsch J. PLoS Biol. 2020, 18 (6), e3000722.
PMID: 32569301
Peritoneal GATA6+ Macrophages Function as a Portal for Staphylococcus Aureus Dissemination.
Jorch SK, Surewaard BGJ, Hossain M, Peiseler M, Deppermann C, Deng J, Bogoslowski A, van der Wal F, Omri A, Hickey MJ, Kubes P. J. Clin. Invest. 2019, 129 (11), 4643–4656.
PMID: 31545300
HIF1A and NFAT5 Coordinate Na+-Boosted Antibacterial Defense via Enhanced Autophagy and Autolysosomal Targeting.
Neubert P, Weichselbaum A, Reitinger C, Schatz V, Schröder A, Ferdinand JR, Simon M, Bär AL, Brochhausen C, Gerlach RG, Tomiuk S, Hammer K, Wagner S, van Zandbergen G, Binger KJ, Müller DN, Kitada K, Clatworthy MR, Kurts C, Titze J, Abdullah Z, Jantsch J. Autophagy 2019, 15(11), 1899-1916.
PMID: 30982460
Salt, Inflammation, IL-17 and Hypertension.
Wenzel UO, Bode M, Kurts C, Ehmke H. Br. J. Pharmacol. 2019, 176 (12), 1853–1863.
PMID: 29767465
Extracellular Vesicles in Liver Diseases: Meeting Report from the International Liver Congress 2018.
Banales JM, Feldstein AE, Sänger H, Lukacs-Kornek V, Szabo G, Kornek M. Hepatol. Commun. 2019, 3 (2), 305–315.
PMID: 30766966
Enzymatic Activity of HPGD in Treg Cells Suppresses Tconv Cells to Maintain Adipose Tissue Homeostasis and Prevent Metabolic Dysfunction.
Schmidleithner L, Thabet Y, Schönfeld E, Köhne M, Sommer D, Abdullah Z, Sadlon T, Osei-Sarpong C, Subbaramaiah K, Copperi F, Haendler K, Varga T, Schanz O, Bourry S, Bassler K, Krebs W, Peters AE, Baumgart AK, Schneeweiss M, Klee K, Schmidt SV, Nüssing S, Sander J, Ohkura N, Waha A, Sparwasser T, Wunderlich FT, Förster I, Ulas T, Weighardt H, Sakaguchi S, Pfeifer A, Blüher M, Dannenberg AJ, Ferreirós N, Muglia LJ, Wickenhauser C, Barry SC, Schultze JL, Beyer M. Immunity 2019, 50 (5), 1232-1248.e14.
PMID: 31027998
