Publications

Transcriptional regulator SATB1 limits CD8+ T cell population expansion and effector differentiation in chronic infection and cancer.
Heyden L, Rausch L, Shannon MH, Dryburgh L, Moreira ML, Frolov A, Scheffler CM, Van Elsas MJ, Tong J, Hidajat O, Wijesinghe SKM, Li S, Horvatic H, Huynh-Anh NT, Gago Da Graça C, Tsui C, Köhne M, Sommer D, Wunderlich FT, Von Scheidt B, Park SL, Mackay LK, Utzschneider DT, Schröder J, Turner SJ, Darcy PK, Beyer MD, Abdullah Z, Kallies A.
Nat Immunol

PMID: 41145844

Stem-like tissue-resident memory T cells control functional heterogeneity and reactivation of T cell memory in the intestine.
Man K, Duarte Da Silva VA, Potemkin N, Gabriel SS, Mason T, Elmzzahi T, De Lima Moreira M, Su CH, Mackay L, Beyer MD, Schröder J, Gasteiger G, Kallies A.
Sci Immunol

PMID: 41171881

Low-dose glucocorticoids attenuate crescentic glomerulonephritis by inhibiting the local differentiation of proinflammatory neutrophils.
Yin J, Eichler M, Schaub DP, Asada N, Engesser J, Lisowski C, Paust HJ, Weisheit CK, Li J, Klaus D, Garbi N, Von Vietinghoff S, Krebs CF, Panzer U, Kurts C.
Sci Transl Med

PMID: 41091917

Residence of mice in metabolic cages reduces experimental kidney inflammation through stress-induced glucocorticoids

Yin J, Eichler M, Lisowski C, Li J, Von Vietinghoff S, Garbi N, Mei Q, Gellner AK, Kurts C
JCI Insight

PMID: 40198131

Kidney immunology from pathophysiology to clinical translation

Kurts C, Von Vietinghoff S, Krebs CF, Panzer U
Nat Rev Immunol

PMID: 39885266

Dual Fluorescence Reporter Mice for Ccl3 Transcription, Translation, and Intercellular Communication

Rodrigo MB, De Min A, Jorch SK, Martin-Higueras C, Baumgart AK, Goldyn B, Becker S, Garbi N, Lemmermann NA, Kurts C
J Exp Med

PMID: 38661718

Determining Individual Glomerular Proteinuria and Periglomerular Infiltration in a Cleared Murine Kidney by a 3-Dimensional Fast Marching Algorithm.

Böhner AMC, Effland A, Jacob AM, Böhner KAM, Abdullah Z, Brähler S, Attenberger UI, Rumpf M, Kurts C.
Kidney Int

PMID: 38458475

Increased Type-I Interferon Level Is Associated with Liver Damage and Fibrosis in Primary Sclerosing Cholangitis.

Salzmann RJS, Krötz C, Mocan T, Mocan LP, Grapa C, Rottmann S, Reichelt R, Keller CM, Langhans B, Schünemann F, Pohl A, Böhler T, Bersiner K, Krawczyk M, Milkiewicz P, Sparchez Z, Lammert F, Gehlert S, Gonzalez-Carmona M A, Willms A, Strassburg CP, Kornek MT, Dold L, Lukacs-Kornek V. 
Hepatol Commun

PMID: 38358371

Rapid Protection against Viral Infections by Chemokine-Accelerated Post-Exposure Vaccination. 

Heine A, Lemmermann NAW, Flores C, Becker-Gotot J, Garbi N, Brossart P, Kurts C.
Front Immunol

PMID: 38348028

Opposing roles of resident and infiltrating immune cells in the defense against Legionella longbeachae via IL-18R/IFN-γ/ROS axis in mice 

Oberkircher LM, Scheiding VM, Rafeld HL, Hanssen E, Hansen JN, Fleischmann MJ, Kessler N, Pitsch D, Wachten D, Kastenmüller W, Brown AS, Hartland EL, van Driel IR, Ng GZ, Garbi N
Mucosal Immunol

PMID: 38750967

Conditional NKT Cell Depletion in Mice Reveals a Negative Feedback Loop That Regulates CTL Cross-Priming.

Heuser-Loy C, Baumgart AK, Hackstein CP, Courrèges CJF, Philipp MS, Thaiss CA, Holland T, Evaristo C, Garbi N, Kurts C. J. Immunol. 2023, ji2300662. https://doi.org/10.4049/jimmunol.2300662.

PMID: 38019126

Mucosal-Associated Invariant T Cells Contribute to Suppression of Inflammatory Myeloid Cells in Immune-Mediated Kidney Disease.

Gnirck AC, Philipp MS, Waterhölter A, Wunderlich M, Shaikh N, Adamiak V, Henneken L, Kautz T, Xiong T, Klaus D, Tomczyk P, Al-Bahra MM, Menche D, Walkenhorst M, Lantz O, Willing A, Friese MA, Huber TB, Krebs CF, Panzer U, Kurts C, Turner JE. Nat. Commun. 2023, 14 (1), 7372. https://doi.org/10.1038/s41467-023-43269-0

PMID: 37968302

The Endosomal System of Primary Human Vascular Endothelial Cells and Albumin–FcRn Trafficking. 

Pannek A, Becker-Gotot J, Dower SK, Verhagen AM, Gleeson PA. J. Cell Sci. 2023, 136 (15), jcs260912. https://doi.org/10.1242/jcs.260912.

PMID: 37565427

Fate Mapping Reveals Compartment-Specific Clonal Expansion of Mononuclear Phagocytes during Kidney Disease

Yin J, Mei Q, Prinz M, Abdullah Z, Panzer U, Li J, Von Vietinghoff S, Kurts C. Kidney Int. 2023, S0085253823004015. https://doi.org/10.1016/j.kint.2023.04.031.

PMID: 37290602

Cigarette Smoke Depletes Alveolar Macrophages and Delays Clearance of Legionella Pneumophila. 

Fleischmann M, Jarnicki AG, Brown AS, Yang C, Anderson GP, Garbi N, Hartland EL, van Driel IR, Ng GZ. Am. J. Physiol. Lung Cell. Mol. Physiol. 2023. https://doi.org/10.1152/ajplung.00268.2022.

PMID: 36719079

Potentially Improved Response of COVID-19 Vaccinated Nasopharyngeal Cancer Patients to Combination Therapy with Anti-PD-1 Blockade and Chemotherapy.
Hua Y J, Liu YL, Wen K, Kurts C, Wu H, Mei Q, Li J. Ann. Oncol. 2022, S0923753422041886. https://doi.org/10.1016/j.annonc.2022.10.002

PMID: 36216192

Immune Tolerance against Infused FVIII in Hemophilia A Is Mediated by PD-L1+ Regulatory T Cells.
Becker-Gotot J,  Meissner M, Kotov V, Jurado-Mestre B, Maione A, Pannek A, Albert T, Flores C, Schildberg FA, Gleeson PA, Reipert BM, Oldenburg J, Kurts C. J. Clin. Invest. 2022 https://doi.org/10.1172/JCI159925.
PMID: 36107620

Monocyte-Derived Macrophages Aggravate Pulmonary Vasculitis via CGAS/STING/IFN-Mediated Nucleic Acid Sensing. 

Kessler N, Viehmann SF, Krollmann C, Mai K, Kirschner KM, Luksch H, Kotagiri P, Böhner AMC, Huugen D, de Oliveira Mann CC, Otten S, Weiss SAI, Zillinger T, Dobrikova K, Jenne DE, Behrendt R, Ablasser A, Bartok E, Hartmann G, Hopfner KP, Lyons PA, Boor P, Rösen-Wolff A, Teichmann LL, Heeringa P, Kurts C, Garbi N. J. Exp. Med. 2022, 219 (10), e20220759.

PMID: 35997679

Generation of an Alpaca Serum That Induces Immune-Mediated Crescentic Glomerulonephritis in Mice.

Dhana E, Klaus D, Böhner A, Schmidt F, von Vietinghoff S, Boor P, Djudjaj S, Kurts C. J. Immunol. Methods 2022, 507, 113310

PMID: 35787393

Impact of COVID-19 vaccination on the use of PD-1 inhibitor in treating patients with cancer: a real-world study

Mei Q, Hu G, Yang Y,  Liu B, Yin J, Li M, Huang Q, Tang X, Böhner A, Bryant A, Kurts C, Yuan X, Li, J. J Immunother Cancer 2022 Mar;10(3):e004157.

PMID: 35264438