Publications

Cigarette Smoke Depletes Alveolar Macrophages and Delays Clearance of Legionella Pneumophila. 

Fleischmann M, Jarnicki AG, Brown AS, Yang C, Anderson GP, Garbi N, Hartland EL, van Driel IR, Ng GZ. Am. J. Physiol. Lung Cell. Mol. Physiol. 2023. https://doi.org/10.1152/ajplung.00268.2022.

PMID: 36719079

Interferon-Induced IL-10 Drives Systemic T-Cell Dysfunction during Chronic Liver Injury.

Hackstein CP, Spitzer J, Symeonidis K, Horvatic H, Bedke T, Steglich B, Klein S, Assmus LM, Odainic A, Szlapa J, Kessler N, Beyer M, Schmithausen R, Latz E, Flavell RA, Garbi N, Kurts C, Kümmerer BM, Trebicka J, Roers A, Huber S, Schmidt SV, Knolle P.A, Abdullah Z. J. Hepatol. 2023, S0168827823001587. https://doi.org/10.1016/j.jhep.2023.02.026.

PMID: 36870611

Complex Regulation of Alarmins S100A8/A9 and Secretion via Gasdermin D Pores Exacerbates Autoinflammation in Familial Mediterranean Fever.

Jorch SK, McNally A, Berger P, Wolf J, Kaiser K, Chetrusca Covash A, Robeck S, Pastau I, Fehler O, Jauch-Speer SL, Hermann S, Schäfers M, Van Gorp H, Kanneganti A, Dehoorne J, Haerynck F, Penco F, Gattorno M, Chae JJ, Kubes P, Lamkanfi M, Wullaert A, Sperandio M, Vogl T, Roth J, Austermann J. J. Allergy Clin. Immunol. 2023, S0091674923002257. https://doi.org/10.1016/j.jaci.2023.01.037.

PMID: 36822481

Potentially Improved Response of COVID-19 Vaccinated Nasopharyngeal Cancer Patients to Combination Therapy with Anti-PD-1 Blockade and Chemotherapy.
Hua Y J, Liu YL, Wen K, Kurts C, Wu H, Mei Q, Li J. Ann. Oncol. 2022, S0923753422041886. https://doi.org/10.1016/j.annonc.2022.10.002

PMID: 36216192

Immune Tolerance against Infused FVIII in Hemophilia A Is Mediated by PD-L1+ Regulatory T Cells.
Becker-Gotot J,  Meissner M, Kotov V, Jurado-Mestre B, Maione A, Pannek A, Albert T, Flores C, Schildberg FA, Gleeson PA, Reipert BM, Oldenburg J, Kurts C. J. Clin. Invest. 2022 https://doi.org/10.1172/JCI159925.
PMID: 36107620

Monocyte-Derived Macrophages Aggravate Pulmonary Vasculitis via CGAS/STING/IFN-Mediated Nucleic Acid Sensing. 

Kessler N, Viehmann SF, Krollmann C, Mai K, Kirschner KM, Luksch H, Kotagiri P, Böhner AMC, Huugen D, de Oliveira Mann CC, Otten S, Weiss SAI, Zillinger T, Dobrikova K, Jenne DE, Behrendt R, Ablasser A, Bartok E, Hartmann G, Hopfner KP, Lyons PA, Boor P, Rösen-Wolff A, Teichmann LL, Heeringa P, Kurts C, Garbi N. J. Exp. Med. 2022, 219 (10), e20220759.

PMID: 35997679

Generation of an Alpaca Serum That Induces Immune-Mediated Crescentic Glomerulonephritis in Mice.

Dhana E, Klaus D, Böhner A, Schmidt F, von Vietinghoff S, Boor P, Djudjaj S, Kurts C. J. Immunol. Methods 2022, 507, 113310

PMID: 35787393

Impact of COVID-19 vaccination on the use of PD-1 inhibitor in treating patients with cancer: a real-world study

Mei Q, Hu G, Yang Y,  Liu B, Yin J, Li M, Huang Q, Tang X, Böhner A, Bryant A, Kurts C, Yuan X, Li, J. J Immunother Cancer 2022 Mar;10(3):e004157.

PMID: 35264438

Health Issues and Immunological Assessment Related to Wuhan’s COVID-19 Survivors: A Multicenter Follow-Up Study. 

Mei Q, Wang F, Yang Y,  Hu G, Guo S, Zhang Q, Bryant A, Zhang L, Kurts C, Wei L, Yuan X, Li, J. Front. Med. 2021, 8, 617689. 

PMID: 34026775

Regulation and Function of CX3CR1 and Its Ligand CX3CL1 in Kidney Disease.

von Vietinghoff S, Kurts C. 

PMID: 34009468

Sodium and Its Manifold Impact on Our Immune System. 

Jobin K, Müller DN, Jantsch J, Kurts C. Trends Immunol. 2021, 42 (6), 469–479. 

PMID: 33962888

Survival Factors and Metabolic Pathogenesis in Elderly Patients (≥65) With COVID-19: A Multi-Center Study. 

Mei Q, Wang AY, Bryant A, Yang Y, Li M, Wang F, Du S, Kurts C, Wu P, Ma K, Wu L, Chen H, Luo J, Li Y, Hu G, Yuan X, Li J. Front. Med. 2021, 7, 595503.

PMID: 33585504

Vascular Pathologies in Chronic Kidney Disease: Pathophysiological Mechanisms and Novel Therapeutic Approaches.

Düsing P, Zietzer A, Goody PR, Hosen MR, Kurts C, Nickenig G, Jansen F. J. Mol. Med. 2021, 99 (3), 335–348. 

PMID: 33481059

A High-Salt Diet Compromises Antibacterial Neutrophil Responses through Hormonal Perturbation.

Jobin K, Stumpf NE, Schwab S, Eichler M, Neubert P, Rauh M, Adamowski M, Babyak O, Hinze D, Sivalingam S, Weisheit C, Hochheiser K, Schmidt SV, Meissner M, Garbi N, Abdullah Z, Wenzel U, Hölzel M, Jantsch J, Kurts C. Sci. Transl. Med. 2020, 12 (536), eaay3850.

PMID: 32213629

Splenic Red Pulp Macrophages Cross-Prime Early Effector CTL That Provide Rapid Defense against Viral Infections.

Enders M, Franken L, Philipp MS, Kessler N, Baumgart AK, Eichler M, Wiertz EJH, Garbi N, Kurts C. J. Immunol. 2020, 204 (1), 87–100. 

PMID: 31776205

Development and Validation of Prognostic Model for Predicting Mortality of COVID-19 Patients in Wuhan, China.

Mei Q, Wang AY, Bryant A, Yang Y, Li M, Wang F, Zhao JW, Ma K, Wu L, Chen H, Luo J, Du S, Halfter K, Li Y, Kurts C, Hu G, Yuan X, Li J. Sci. Rep. 2020, 10 (1), 22451

PMID: 33384422

Pathogen-Induced Tissue-Resident Memory T_H17 (T_RM17) Cells Amplify Autoimmune Kidney Disease.

Krebs CF, Reimers D, Zhao Y, Paust HJ, Bartsch P, Nuñez S, Rosemblatt MV, Hellmig M, Kilian C, Borchers A, Enk LUB, Zinke M, Becker M, Schmid J, Klinge S, Wong MN, Puelles VG, Schmidt C, Bertram T, Stumpf N, Hoxha E, Meyer-Schwesinger C, Lindenmeyer MT, Cohen CD, Rink M, Kurts C, Franzenburg S, Koch-Nolte F, Turner JE, Riedel JH, Huber S, Gagliani N, Huber TB, Wiech T, Rohde H, Bono MR, Bonn S, Panzer U, Mittrücker HW. Sci. Immunol. 2020, 5 (50).

PMID: 32769171

NCX1 Represents an Ionic Na⁺ Sensing Mechanism in Macrophages. 

Neubert P, Homann A, Wendelborn D, Bär AL, Krampert L, Trum M, Schröder A, Ebner S, Weichselbaum A, Schatz V, Linz P, Veelken R, Schulte-Schrepping J, Aschenbrenner AC, Quast T, Kurts C, Geisberger S, Kunzelmann K, Hammer K, Binger KJ, Titze J, Müller DN, Kolanus W, Schultze JL, Wagner S, Jantsch J. PLoS Biol. 2020, 18 (6), e3000722.

PMID: 32569301